Coenzyme Q100
Co-Q-100®
(100 mg)
Thorne Research
Information:
Coenzyme
Q10, a quinone; also called
ubiquinone, is related to Vitamin K. Coenzyme Q10 naturally occurs in
the body and is a particularly important factor in mitochondrial energy
synthesis. Coenzyme Q10 acts as a cofactor in the electron transport chain
that creates adenosine triphosphate (ATP). ATP is the body's major source
of energy to fuel its biochemical reactions. With bioenergetic inhibition
of mitochondrial function, Co-Q10 becomes conditionally essential. Simply
stated, when the body is exhausted by fighting disease, Co-Q10 is beneficial
as a supplement, enhancing all body functions. Due to its energy-producing
effect, coenzyme Q10 may help boost the immune system in energy deficient
individuals. This might include conditions such as:
1.
Chronic disease states
2.
Inflammation, especially gingivitis1
3.
Cardiomyopathy2,3
Coenzyme
Q10 supplementation has been shown to boost antibody production and enhance
phagocytosis4,5.
Cells that benefit
the most from the addition of coenzyme Q10 are those that have a more
rapid turnover, including heart, gingiva, mucosal cells of the intestines,
and immune system cells. Known benefits for coenzyme Q10 include treatment
of periodontal disease1, lymphocytic gingivitis, and any heart
disease2 that is associated with poor contraction3.
Diabetics are commonly reported to be deficient in coenzyme Q10, and benefit
from its supplementation.
Dietary
sources for coenzyme Q10 include migratory fish (mackerel and sardines),
organ meats, and, to a lesser extent, legumes, rice and canola oil.
Some conditions that may improve with Coenzyme Q10
supplementation include:
1.
Dental disease
2.
Gum disease, gingivitis, inflammation in the mouth
3.
Immune boosting
4.
Diabetes
5.
Heart diseases, including
- cardiomyopathy
- heart murmurs
- enlarged heart
- rapid heart beats (tachycardia)
- irregular heart beats (arrhythmia)
1.
Hanioka T, et al. Effect of topical application of coenzyme Q10 on adult
periodontitis. Mol Aspects Med.;15 Suppl:s241:8, 1994.
2.
Lonnrot K ; Tolvanen JP ; Porsti I ; Ahola T ; Hervonen A ;Alho H. Coenzyme
Q10 supplementation and recovery from ischemia in senescent rat myocardium.
Life Sci;64(5):315:23, 1999.
3.
Sunamori M, et al.Clinical experience of coenzyme Q10 to enhance intraoperative
myocardial protection in coronary artery revascularization. Cardiovasc
Drugs Ther. Mar; 5 Suppl 2:297:300, 1991.
4.
Novoselova EG, et al. Immune functions of spleen lymphocytes of rats subjected
to chronic irradiation and antioxidant (ubiquinone Q-10) diet. Int J Radiat
Biol.;67(4):469:76, Apr 1995.
5. Saiki
I, et al. Macrophage activation with ubiquinones and their related compounds
in mice. Int J Vitam Nutr Res.53(3):312:20, 1983.
Dosage:
Cats:
30
mg twice daily, up to 100 mg for severe situations twice daily
Dogs:
30
mg for each 20 lbs body weight twice daily, most dogs should receive
100-300 mg as a daily dose
Birds:
5
mg twice daily for each 200 grams body weight